Search results for " Carcinogeni"
showing 4 items of 4 documents
Early effects of fluoro-edenite: correlation between IL-18 serum levels and pleural and parenchymal abnormalities.
2016
Fluoro-edenite (FE) is a natural mineral asbestos-like fibrous species first isolated in Biancavilla, Sicily. In order to clarify potential involvement of IL-18 in the pathogenesis of FE-induced chest abnormalities, we analyzed IL-18 serum levels in FE-exposed workers (FEEW) and correlated them with pleural and parenchymal abnormalities. A total of 21 FEEWs, residing in Biancavilla for >30 years, with a working seniority of 17 ± 6.1 years were examined. High-resolution computed tomography scans revealed low grade of fibrosis in 8 (38%) FEEWs, and pleural plaques (PPs) in 13 (62%) FEEWs. The mean IL-18 level was 203.13 ± 90.43 pg/ml. Pearson correlation showed a significant association (…
Contamination from polycyclic aromatic hydrocarbons (PAHs) in the soil of a botanic garden localized next to a former manufacturing gas plant in Pale…
2010
The Botanical Garden lies within the city of Palermo, a few meters away from one of the largest unused Manufacturing Gas Plant in Sicily. The total concentrations of PAHs (23 compounds) in the soil of Botanical Garden ranged from 947 to 18,072 microg/kg. The wide range of PAH concentrations (RSD=84%) found in the soil samples indicates heterogeneous levels of contamination in the area and this can be explained by considering the different tree distributions which prevents the homogeneous deposition of pollutants on the soil. Soils collected in the Botanical Garden generally showed the highest PAH concentrations, being almost 2-3 times higher than the concentration samples obtained in the ur…
The concentration and non-carcinogenic risk assessment of aluminium in fruits, soil, and water collected from Iran
2020
The current study was conducted to investigate the concentration of bio-available aluminium (Al) in totally 90 samples of five types of fruits (grape, apple, nectarine, plum, and peach), the water ...
Validation of the SOS/umu test using test results of 486 chemicals and comparison with the Ames test and carcinogenicity data
1996
The present study gives a comprehensive update of all umu genotoxicity assay results published so far. The available data of 486 chemicals investigated with the umu test are compared with the Ames test (274 compounds) as well as rodent carcinogenicity data (179 compounds). On the whole, there is good agreement between the umu test and the Ames test results, with a concordance of about 90%. The umu test was able to detect 86% of the Ames mutagens, while the Ames test (using at least 5 strains) detected 97% of the umu positive compounds. The elimination of TA102 from the set of Ames tester strains reduced the percentage of detectable umu genotoxins from 97 to 86%. The agreement between carcin…